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Table 1 Demographic and biomarker features of this population

From: Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study

 

Aβ-PET (−)

Aβ-PET (+)

p value

N (%)

41 (69.5%)

18 (30.5%)

 

Age, mean (SD)

71.6 (4.11)

75.2 (5.65)

p 0.014

Gender Female, n (%)

18 (43.9%)

9 (50.0%)

p 0.665

APOE4 carriers, n (%)

6 (14.6%)

12 (66.7%)

p < 0.001

Education level, mean years (SD)

12.33 (3.96)

10.56 (4.44)

p 0.113

CN/a-MCI, n (% a-MCI)

35/6 (14.6%)

4/14 (77.8%)

p < 0.001

TP42/40, mean (SD)

0.1329 (0.0208)

0.0997 (0.0197)

p < 0.001

AD-Conv score, mean (SD)

0.133 (0.162)

0.384 (0.259)

p < 0.001

  1. p value was obtained from Mann-Whitney or chi-squared tests as appropriate. SD standard deviation, CN cognitively normal, a-MCI amnestic mild cognitive impairment, amyloid-beta, TP42/40 total plasma Aβ42/40 ratio, AD-Conv score AD conversion score based on FDG-PET