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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Age-dependent emergence of neurophysiological and behavioral abnormalities in progranulin-deficient mice

Fig. 2

Impaired conductivity of the MD-mPFC pathway in progranulin-deficient mice. The latency of the first positive deflection (P10) in EFPs for WT, heterozygous (Grn+/−), and homozygous (Grn−/−) mice. a No significant differences in latency among the genotypes at 3 months. b, c Latency was significantly greater in heterozygous mice at 6.5 and 12.5 months. Data are expressed as the mean ± SEM. Differences in normalized amplitude were considered significant when p < 0.05

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Alzheimer's Research & Therapy

ISSN: 1758-9193