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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Midlife physical activity is associated with lower incidence of vascular dementia but not Alzheimer’s disease

Fig. 3

The effect of running on AD pathology in the 5xFAD mouse model. The effect on cognitive function (a), synaptic proteins (b) in the hippocampus, amyloid-β levels in the cortex and hippocampus (c), and Aβ-species in the hippocampus (d). Box plot represents the median values for each group with interquartile ranges and error bars indicating the minimum and maximum. *p < 0.05 in Mann-Whitney U test. For cognitive tests, n = 13–14 in each group; for amyloid-β and synaptic proteins, n = 9–14 in each group

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