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Table 2 Macular retinal thickness in the overall cohort for PCA, tAD and control groups

From: Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

  Posterior cortical atrophy (n = 23) Typical Alzheimer’s disease (n = 22) Controls (n = 66) PCA tAD
Beta p value Beta p value
Total macular retinal thickness (mRT) 266.9 (±16.3) 267.8 (±13.6) 269.3 (±13.6) − 0.07 0.50 − 0.09 0.38
Fovea 223.0 (±19.1) 227.7 (±21.5) 224.3 (±23.8) − 0.02 0.80 0.01 0.89
Superior inner 286.8 (±20.3) 289.6 (±15.9) 290.0 (±18.9) − 0.07 0.49 − 0.06 0.56
Temporal inner 276.0 (±17.0) 278.2 (±12.1) 276.0 (±17.4) 0.00 1.00 0.01 0.92
Inferior inner 287.8 (±18.3) 288.0 (±11.5) 289.6 (±17.2) − 0.04 0.68 − 0.09 0.35
Nasal inferior 286.5 (±19.8) 287.9 (±15.1) 289.5 (±19.8) − 0.06 0.53 − 0.08 0.38
Superior outer 263.4 (±18.2) 269.3 (±20.4) 268.4 (±15.5) − 0.12 0.23 − 0.01 0.89
Temporal outer 246.2 (±15.9) 246.8 (±13.9) 247.7 (±14.8) − 0.04 0.67 − 0.06 0.57
Inferior outer 259.0 (±19.8) 258.6 (±14.5) 261.3 (±15.2) − 0.05 0.60 − 0.09 0.35
Nasal outer 281.3 (±17.8) 280.5 (±16.7) 285.0 (±16.1) − 0.08 0.40 − 0.14 0.15
Signal to noise ratio 8.6 (±0.8) 8.6 (±0.7) 8.4 (±0.8) 0.11 0.26 0.10 0.34
  1. Total macular retinal thickness (mRT) in Early Treatment in Diabetes Retinopathy Study (ETDRS) regions in posterior cortical atrophy (PCA), typical Alzheimer’s disease (tAD) and control participants. Means (±SD) are shown together with standardized betas and p-values from linear regression models with macular measures as dependent variable and diagnosis as an independent variable, adjusted for age and sex