Skip to main content

Table 2 Macular retinal thickness in the overall cohort for PCA, tAD and control groups

From: Retinal thickness as potential biomarker in posterior cortical atrophy and typical Alzheimer’s disease

 

Posterior cortical atrophy (n = 23)

Typical Alzheimer’s disease (n = 22)

Controls

(n = 66)

PCA

tAD

Beta

p value

Beta

p value

Total macular retinal thickness (mRT)

266.9 (±16.3)

267.8 (±13.6)

269.3 (±13.6)

− 0.07

0.50

− 0.09

0.38

Fovea

223.0 (±19.1)

227.7 (±21.5)

224.3 (±23.8)

− 0.02

0.80

0.01

0.89

Superior inner

286.8 (±20.3)

289.6 (±15.9)

290.0 (±18.9)

− 0.07

0.49

− 0.06

0.56

Temporal inner

276.0 (±17.0)

278.2 (±12.1)

276.0 (±17.4)

0.00

1.00

0.01

0.92

Inferior inner

287.8 (±18.3)

288.0 (±11.5)

289.6 (±17.2)

− 0.04

0.68

− 0.09

0.35

Nasal inferior

286.5 (±19.8)

287.9 (±15.1)

289.5 (±19.8)

− 0.06

0.53

− 0.08

0.38

Superior outer

263.4 (±18.2)

269.3 (±20.4)

268.4 (±15.5)

− 0.12

0.23

− 0.01

0.89

Temporal outer

246.2 (±15.9)

246.8 (±13.9)

247.7 (±14.8)

− 0.04

0.67

− 0.06

0.57

Inferior outer

259.0 (±19.8)

258.6 (±14.5)

261.3 (±15.2)

− 0.05

0.60

− 0.09

0.35

Nasal outer

281.3 (±17.8)

280.5 (±16.7)

285.0 (±16.1)

− 0.08

0.40

− 0.14

0.15

Signal to noise ratio

8.6 (±0.8)

8.6 (±0.7)

8.4 (±0.8)

0.11

0.26

0.10

0.34

  1. Total macular retinal thickness (mRT) in Early Treatment in Diabetes Retinopathy Study (ETDRS) regions in posterior cortical atrophy (PCA), typical Alzheimer’s disease (tAD) and control participants. Means (±SD) are shown together with standardized betas and p-values from linear regression models with macular measures as dependent variable and diagnosis as an independent variable, adjusted for age and sex