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Table 2 Prevalence and group differences in SCD-plus features and SCD-I domains

From: Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study

N = 205

Sample

Chi2/F value; p value

 

Total Sample

HC (n = 76)

SCD (n = 105)

Relatives of AD (n = 24)

SCD-plus features

 Decline in memory

Yes, n (%)

129 (62.9)

20 (26.3)

98 (93.3)

11 (45.8)

88.285***, p < .001

No, n (%)

76 (37.1)

56 (73.7)

7 (6.7)

13 (54.2)

 Onset of SCD in any domain within the last 5 years

Yes, n (%)

120 (58.5)

24 (44.5)

85 (81.0)

11 (45.8)

46.088***, p < .001

No, n (%)

85 (41.5)

52 (68.4)

20 (19.0)

13 (54.2)

 Particular concerns/worries in any domain

Yes, n (%)

113 (55.1)

11 (14.5)

95 (90.5)

7 (29.2)

110.351***, p < .001

No, n (%)

92 (44.9)

65 (85.5)

10 (9.5)

17 (70.8)

 The feeling of worse performance than others in any domain

Yes, n (%)

35 (17.1)

1 (1.3)

31 (29.5)

3 (12.5)

25.179***, p < .001

No, n (%)

170 (82.9)

75 (98.7)

74 (70.5)

21 (87.5)

 Confirmation of decline in any domain by an informanta

Yes, n (%)

81 (39.5)

15 (39.47)

59 (57.84)

7 (43.75)

25.731***, p < .001

No, n (%)

124 (60.5)

61 (60.53)

46 (42.16)

17 (56.25)

Number of fulfilled SCD-plus features

M (SD)

2.33 (1.73)

0.9 (1.27)

3.5 (1.08)

1.63 (1.71)

99.81***, p < .001

SCD-I domains

 Decline in memory

Yes, n (%)

129 (62.9)

20 (26.3)

98 (93.3)

11 (45.8)

88.285***, p < .001

No, n (%)

76 (37.1)

56 (73.7)

7 (6.7)

13 (54.2)

 Decline in language

Yes, n (%)

127 (62.0)

28 (36.8)

87 (82.9)

12 (50)

41.251***, p < .001

No, n (%)

78 (38.0)

48 (63.2)

18 (17.1)

12 (50)

 Decline in attention

Yes, n (%)

62 (30.2)

6 (7.9)

49 (46.7)

7 (29.2)

31.430***, p < .001

No, n (%)

143 (69.8)

70 (92.1)

56 (53.3)

17 (70.8)

 Decline in planning

Yes, n (%)

20 (9.8)

2 (2.6)

22 (21.0)

2 (8.3)

13.827***, p < .001

No, n (%)

6 (2.9)

74 (97.4)

83 (79.0)

22 (91.7)

 Decline in other

Yes, n (%)

48 (23.5)

5 (6.6)

39 (37.1)

4 (16.7)

24.045***, p < .001

No, n (%)

156 (76.1)

71 (93.4)

65 (61.9)

20 (83.3)

Number of reported SCD domains

M (SD)

1.91 (1.47)

0.80 (0.98)

2.81 (1.17)

1.50 (1.44)

70.17***, p < .001

  1. *p < .05
  2. **p < .01
  3. ***p < .001
  4. aThis refers to participants reporting a decline in at least one domain including a total of n = 156 (76.1%) individuals (HC: n = 38 (50%); SCD: n = 102 (97.1%); AD relatives n = 16 (66.7%))