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Table 2 Prevalence and group differences in SCD-plus features and SCD-I domains

From: Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study

N = 205 Sample Chi2/F value; p value
  Total Sample HC (n = 76) SCD (n = 105) Relatives of AD (n = 24)
SCD-plus features
 Decline in memory Yes, n (%) 129 (62.9) 20 (26.3) 98 (93.3) 11 (45.8) 88.285***, p < .001
No, n (%) 76 (37.1) 56 (73.7) 7 (6.7) 13 (54.2)
 Onset of SCD in any domain within the last 5 years Yes, n (%) 120 (58.5) 24 (44.5) 85 (81.0) 11 (45.8) 46.088***, p < .001
No, n (%) 85 (41.5) 52 (68.4) 20 (19.0) 13 (54.2)
 Particular concerns/worries in any domain Yes, n (%) 113 (55.1) 11 (14.5) 95 (90.5) 7 (29.2) 110.351***, p < .001
No, n (%) 92 (44.9) 65 (85.5) 10 (9.5) 17 (70.8)
 The feeling of worse performance than others in any domain Yes, n (%) 35 (17.1) 1 (1.3) 31 (29.5) 3 (12.5) 25.179***, p < .001
No, n (%) 170 (82.9) 75 (98.7) 74 (70.5) 21 (87.5)
 Confirmation of decline in any domain by an informanta Yes, n (%) 81 (39.5) 15 (39.47) 59 (57.84) 7 (43.75) 25.731***, p < .001
No, n (%) 124 (60.5) 61 (60.53) 46 (42.16) 17 (56.25)
Number of fulfilled SCD-plus features M (SD) 2.33 (1.73) 0.9 (1.27) 3.5 (1.08) 1.63 (1.71) 99.81***, p < .001
SCD-I domains
 Decline in memory Yes, n (%) 129 (62.9) 20 (26.3) 98 (93.3) 11 (45.8) 88.285***, p < .001
No, n (%) 76 (37.1) 56 (73.7) 7 (6.7) 13 (54.2)
 Decline in language Yes, n (%) 127 (62.0) 28 (36.8) 87 (82.9) 12 (50) 41.251***, p < .001
No, n (%) 78 (38.0) 48 (63.2) 18 (17.1) 12 (50)
 Decline in attention Yes, n (%) 62 (30.2) 6 (7.9) 49 (46.7) 7 (29.2) 31.430***, p < .001
No, n (%) 143 (69.8) 70 (92.1) 56 (53.3) 17 (70.8)
 Decline in planning Yes, n (%) 20 (9.8) 2 (2.6) 22 (21.0) 2 (8.3) 13.827***, p < .001
No, n (%) 6 (2.9) 74 (97.4) 83 (79.0) 22 (91.7)
 Decline in other Yes, n (%) 48 (23.5) 5 (6.6) 39 (37.1) 4 (16.7) 24.045***, p < .001
No, n (%) 156 (76.1) 71 (93.4) 65 (61.9) 20 (83.3)
Number of reported SCD domains M (SD) 1.91 (1.47) 0.80 (0.98) 2.81 (1.17) 1.50 (1.44) 70.17***, p < .001
  1. *p < .05
  2. **p < .01
  3. ***p < .001
  4. aThis refers to participants reporting a decline in at least one domain including a total of n = 156 (76.1%) individuals (HC: n = 38 (50%); SCD: n = 102 (97.1%); AD relatives n = 16 (66.7%))