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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: An experimental model of Braak’s pretangle proposal for the origin of Alzheimer’s disease: the role of locus coeruleus in early symptom development

Fig. 4

LC axonal degeneration in 11-month-old rats infused with htauE14 at 2–3 months old. a–c LC cell counts in htauE14 and control rats. (N: htau/GFP/non-infused: 7/6/6). d–f NET fibers (red) in the piriform cortex (PC) (N: htau/GFP/non-infused: 6/6/5). g–i DBH fibers (red) in the PC. (N: htau/GFP/non-infused: 6/5/5). j–l β1-adrenoceptors in the PC. (N: htau/GFP: 4/4). m–o Iba-1 in the PC. (N: htau/GFP/non-infused: 6/5/6). LOT, lateral olfactory tract. Scale bars, 50 μm

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Alzheimer's Research & Therapy

ISSN: 1758-9193