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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: An experimental model of Braak’s pretangle proposal for the origin of Alzheimer’s disease: the role of locus coeruleus in early symptom development

Fig. 3

Impairment in go/no-go odor discrimination learning in 10-month-old rats infused with htauE14 at 2–3 months old. a Schematics of the time course of the AAV infusion, odor discrimination training, and histology. b Simple odor discrimination (SOD) training using dissimilar odors. (N: htau/control: 7/7). c Difficult odor discrimination (DOD) training using similar odor pairs. (N: htau/control: 6/5). d Odor habituation/dishabituation test. (N: htau/control: 6/7). MO, mineral oil. O1, odor 1. O2, odor 2

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Alzheimer's Research & Therapy

ISSN: 1758-9193