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Table 3 Beta coefficients obtained from linear regression analyses relating CFC components to reference measures of disease severity

From: Assessing cognition and daily function in early dementia using the cognitive-functional composite: findings from the Catch-Cog study cohort

 

CFI-SP

QoL-AD

ZBI-12

AES

Beta

95% CI

p value

Beta

95% CI

p value

Beta

95% CI

p value

Beta

95% CI

p value

Model 1

 CFC score

.61

.48

.74

< .001

.51

.37

.65

< .001

− .51

− .65

− .37

< .001

− .36

− .51

− .20

< .001

 Age

.14

.02

.27

.028

− .06

− .20

.08

.388

− .08

− .21

.06

.280

− .01

− .16

.14

.913

 Sex

.21

.08

.34

.002

.10

− .04

.24

.171

− .19

− .33

− .05

.009

− .19

− .34

− .04

.014

 Education

− .04

− .17

.09

.578

− .13

− .27

.02

.087

.20

.06

.34

.006

.05

− .10

.21

.507

Model 2

 Cognitive composite

− .09

− .24

.06

.226

− .10

− .26

.07

.254

− .02

− .19

.15

.815

− .01

− .20

.18

.915

 A-IADL-Q

.72

.58

.86

< .001

.62

.46

.77

< .001

− .52

− .68

− .36

< .001

− .37

− .55

− .19

< .001

 Age

.11

− .01

.23

.066

− .09

− .22

.04

.182

− .06

− .19

.08

.409

.01

− .14

.16

.945

 Sex

.18

.06

.30

.004

.07

− .06

.20

.305

− .17

− .31

− .03

.017

− .18

− .33

− .03

.021

 Education

.04

− .09

.16

.552

− .06

− .20

.08

.405

.16

.02

.30

.030

.02

− .14

.18

.791

  1. Abbreviations: AES Apathy Evaluation Scale, A-IADL-Q Amsterdam IADL Questionnaire, CFC cognitive-functional composite, CFI-SP Cognitive Function Instrument study partner version, QoL Quality of life, ZBI Zarit Burden Inventory