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Table 3 Beta coefficients obtained from linear regression analyses relating CFC components to reference measures of disease severity

From: Assessing cognition and daily function in early dementia using the cognitive-functional composite: findings from the Catch-Cog study cohort

  CFI-SP QoL-AD ZBI-12 AES
Beta 95% CI p value Beta 95% CI p value Beta 95% CI p value Beta 95% CI p value
Model 1
 CFC score .61 .48 .74 < .001 .51 .37 .65 < .001 − .51 − .65 − .37 < .001 − .36 − .51 − .20 < .001
 Age .14 .02 .27 .028 − .06 − .20 .08 .388 − .08 − .21 .06 .280 − .01 − .16 .14 .913
 Sex .21 .08 .34 .002 .10 − .04 .24 .171 − .19 − .33 − .05 .009 − .19 − .34 − .04 .014
 Education − .04 − .17 .09 .578 − .13 − .27 .02 .087 .20 .06 .34 .006 .05 − .10 .21 .507
Model 2
 Cognitive composite − .09 − .24 .06 .226 − .10 − .26 .07 .254 − .02 − .19 .15 .815 − .01 − .20 .18 .915
 A-IADL-Q .72 .58 .86 < .001 .62 .46 .77 < .001 − .52 − .68 − .36 < .001 − .37 − .55 − .19 < .001
 Age .11 − .01 .23 .066 − .09 − .22 .04 .182 − .06 − .19 .08 .409 .01 − .14 .16 .945
 Sex .18 .06 .30 .004 .07 − .06 .20 .305 − .17 − .31 − .03 .017 − .18 − .33 − .03 .021
 Education .04 − .09 .16 .552 − .06 − .20 .08 .405 .16 .02 .30 .030 .02 − .14 .18 .791
  1. Abbreviations: AES Apathy Evaluation Scale, A-IADL-Q Amsterdam IADL Questionnaire, CFC cognitive-functional composite, CFI-SP Cognitive Function Instrument study partner version, QoL Quality of life, ZBI Zarit Burden Inventory