Fig. 3
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13195-019-0498-8/MediaObjects/13195_2019_498_Fig3_HTML.png)
Cerebral Aβ levels in 15-month-old APP23 mice treated subchronically with saline, rHDL-rApoJ nanodiscs, or free rApoJ. a Cerebral soluble Aβ40 levels. b Cerebral insoluble Aβ40. c Cerebral insoluble Aβ42, detected by ELISA. d Representative images showing ThS-positive vessels and the corresponding quantification in brain sections. e Representative images showing ThS-positive deposits, quantification of the number of ThS-positive deposits per area (px2), and quantification of the mean size of those deposits. f Representative images of anti-Aβ (4G8)-positive deposits in the brain parenchyma, quantification of the number of Aβ-positive deposits per area (px2), and quantification of the mean size of those deposits. Data are expressed as the mean ± SEM. N = 7/group. *p < 0.05; **p < 0.01