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Table 3 Logistic regression analysis of rs8019381 C/T SNP on the AD phenotype considering for age, gender, and APOE ε4 allele

From: Neurexin 3 transmembrane and soluble isoform expression and splicing haplotype are associated with neuron inflammasome and Alzheimer’s disease

Coefficients of bias-reduced logistic regression
Variable Parameter Standard error Wald χ2 P value
Intercept − 13.917 1.528 − 9.107 < 0.0001
Age 0.179 0.020 8.750 < 0.0001
Gender − 0.051 0.416 − 0.123 0.902
APOE ε4 allelea 1.691 0.403268658 4.194 0.000033
rs8019381 genotypeb 3.078 0.968 3.181 0.00157
  1. aFor APOE ε4 allele analyses, ε4 non-carriers were coded as 0 and APOE ε4 carriers were coded as 1
  2. bFor rs8019381 genotype analyses, each SNP was coded as 0 for major allele homozygotes, 0.5 for heterozygotes, and 1 for minor allele homozygotes