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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

Fig. 4

White matter pathology in the optic tract. a At 8 M post-TBI, histopathological analyses were performed on the optic tract, using Iba1 (microglia), NeuroSilver (axonal injury), SMI312 (neurofilament), and GFAP (astrocytes). Representative images for each stain are shown. Scale bar represents 200 μm. b Quantification of (a) was plotted by reporting the density and size of microglia, the stain area of NeuroSilver, the density of neurofilament-positive axonal bulbs, and GFAP immunofluorescence intensity of astrocytes. Data are plotted as mean ± SE with an overlaid scatterplot of individual animals

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