Table 1 Sociodemographic and clinical characteristics of ALFA participants
Sociodemographic and clinical variables (n = 561) | Mean / n | Interquartile range / % |
|---|---|---|
CAIDE-I risk (%) | 1.47 | 0.67–3.22 |
CAIDE-I score (0–15) | 6 | 4–8 |
Age (years) | 58 | 51–64 |
Hypertension, n (%) | 147 | 26.2 |
Hypercholesterolemia, n (%) | 171 | 30.5 |
BMI (kg/m2) | 26.4 | 24.0–29.4 |
Sex (male), n (%) | 219 | 38.9 |
Education (years) | 14 | 11–17 |
Physical exercise, n (%) | ||
Active | 368 | 65.6 |
Not active | 148 | 26.4 |
Not available | 45 | 8.0 |
APOE genotype, n (%) | ||
ε4/ε4 | 71 | 12.7 |
ε4/ε3 | 170 | 30.3 |
ε3/ε3 | 159 | 28.3 |
ε2/ε4 | 45 | 8.0 |
ε2/ε3 | 109 | 19.4 |
ε2/ε2 | 7 | 1.2 |
Family history of AD, n (%) | ||
Maternal | 190 | 33.9 |
Paternal | 91 | 16.2 |
From both | 16 | 2.9 |
None | 245 | 43.7 |
Not available | 19 | 3.4 |
Fazekas Scale, n (%) | ||
Score 0 | 269 | 48.0 |
Score 1 | 247 | 44.0 |
Score 2 | 43 | 7.7 |
Score 3 | 2 | 0.4 |
Total WMH load (cm3) | 1.94 | 1.13–3.69 |
Total WMH load/TIV (%) | 0.14 | 0.08–0.26 |
MMSE | 29 | 28–30 |
Time difference between visit and MRI (days) | 307 | 251–366 |