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Table 2 Variation of calculated Aβ concentrationsa between four parallel immunoprecipitations

From: A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease

  Aβ38 (pg/ml) Aβ40 (pg/ml) Aβ42 (pg/ml)
Mean SD %CV Mean SD %CV Mean SD %CV
Sample 1 54.08 2.38 4.40 207.22 32.06 15.47 20.38 1.45 7.12
Sample 2 54.04 3.39 6.27 216.78 26.08 12.03 23.45 1.94 8.26
Sample 3 55.44 1.19 2.15 201.50 4.50 2.23 20.12 0.43 2.12
Sample 4 46.37 2.01 4.34 162.46 8.15 5.01 18.60 1.29 6.93
Overall mean 52.48 2.24 4.29 196.99 17.70 8.69 20.64 1.28 6.11
  1. amyloid beta, %CV coefficient of variation, SD standard deviation
  2. aIndicated mean concentrations refer to averaged calculated concentrations (pg/ml) in diluted immunoprecipitation eluates without correction for 10-fold dilution before measurement with the Aβ triplex immunoassay