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Fig. 8 | Alzheimer's Research & Therapy

Fig. 8

From: Cerebrospinal fluid synaptosomal-associated protein 25 is a key player in synaptic degeneration in mild cognitive impairment and Alzheimer’s disease

Fig. 8

CSF SNAP-25 and SNAP-25/Aβ42 in relation to brain structure and WMH. Hippocampal volume, ventricular volume, and WMH at baseline (a, e, i) and over time (b, f, j) as a function of baseline CSF SNAP-25 in different diagnostic groups. Hippocampal volume, ventricular volume, and WMH at baseline (c, g, k) and over time (d, h, l) as a function of baseline SNAP-25/Aβ42 in different diagnostic groups. Biomarker levels and ratios are standardized to z scores. Aβ amyloid-β, AD Alzheimer’s disease, CN cognitively normal, pMCI progressive mild cognitive impairment, sMCI stable mild cognitive impairment, SNAP-25 synaptosomal-associated protein 25, WMH white matter hyperintensity

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Alzheimer's Research & Therapy

ISSN: 1758-9193