Table 2 Human induced pluripotent stem cells from mutation carriers and non-carriers enrolled in DIAN
From: Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network
Gene | Family mutation | Mutation status | Donorsa | Ethnicity | Clinical statusb | APOE | Reprogramming method | Donor number |
|---|---|---|---|---|---|---|---|---|
APP | V717L | Positive | 1 | EA | A | 33 | Episomal | F15553 |
V717I | Positive | 1 | EA | A | 33 | Episomal | F16574 | |
Negative | 1 | EA | A | 33 | Episomal | F12462 | ||
PSEN1 | A79V | Positive | 1 | EA | A | 34 | Sendai | F12424 |
Negative | 1 | EA | A | 33 | Sendai | F12436 | ||
H163R | Positive | 1 | EA | A | 34 | Sendai | F11430 | |
Negative | 1 | EA | A | 33 | Sendai | F12442 | ||
G217R | Positive | 1 | EA | A | 24 | Sendai | F12434 | |
Negative | 1 | EA | A | 34 | Sendai | F12445 | ||
PSEN2 | N141I | Positive | 1 | EA | A | 33 | Sendai | F12448 |
Negative | 1 | EA | A | 34 | Sendai | F12468 |