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Table 1 Gene expression microarray data used to infer human hippocampus transcriptional network and AD MR candidates

From: Alzheimer’s disease master regulators analysis: search for potential molecular targets and drug repositioning candidates

GEO ID

Description

Samples (n)

Reference

GSE60862

Gene expression data of 10 regions of postmortem brains originating from 134 neurologically and neuropathologically normal Caucasian individuals

Hippocampus (n = 114)

Trabzuni et al., 2011 [21]

GSE5281

Gene expression data of 6 regions of postmortem brains originating from 33 Alzheimer’s disease and 14 neurologically normal aged individuals

Hippocampus AD individuals (n = 10)

Hippocampus normal individuals (n = 13)

Liang et al., 2007 [22]; Liang et al., 2008 [23]

GSE29378

Gene expression data of the CA1 and CA3 hippocampus regions of postmortem brains from 17 Alzheimer’s disease and 16 neurologically normal aged individuals

Hippocampus AD individuals (CA1 n = 16, CA3 n = 15)

Hippocampus normal individuals (CA1 n = 16, CA3 n = 16)

Miller et al., 2013 [24]

GSE36980

Gene expression data of frontal and temporal cortices and hippocampal regions of postmortem brains originating from 26 Alzheimer’s disease and 62 neurologically normal aged individuals

Hippocampus AD individuals (n = 7)

Hippocampus normal individuals (n = 10)

Hokama et al., 2014 [25]

GSE48350

Gene expression data of 4 regions of postmortem brains originating from 26 Alzheimer’s disease and 33 neurologically normal aged individuals

Hippocampus AD individuals (n = 17)

Hippocampus normal individuals (n = 23)

Berchtold et al., 2013 [26]

  1. AD Alzhimer’s disease, MR master regulator