Table 1 Demographic information and biomarker data

50/50

(46)

70/30

(10)

44/56

(34)

37/63

(19)

56/44

(9)

55/45

(20)

49/51

(45)

63.6

(55.1–71.7)^a

70.3

(56.2–74.4)

63.3

(54.5–71.6)

59.0

(53.7–69.5)*

67.3

(63.3–71.9)

69.4

(61.5–74.7)

71.2

(66.7–79.2)

62.0

(53.8–69.2)^a

56.0

(54.0–71.0)

63.5

(52.8–69.2)

56.0

(48.0–67.0)

66.0

(61.5–70.0)

N/A

69.5

(64.3–75.8)

65.9

(60.2–75.1)

74.0

(60.8–76.2)

62.9

(57.5–72.5)

57.7

(52.3–62.6)*^†

69.1

(61.1–74.2)

N/A

N/A

32.4

(37)

57.1

(7)

27.6

(29)

30.8

(13)

20.0

(10)

33.3

(6)

59.5

(42)

21 (15–25)

(29)

23 (22–27)

(5)

19 (14–25)

(23)

15 (7–21)

(10)^†

23 (16–26)

(7)

N/A

20 (15–25)

(42)

95

(60–126)^a,b

96

(76–167)*

95

(61–125)

107

(91–125)*

48

(39–63)

130

(101–175)

119

(98–145)

3.39

(2.29–3.85)^a

3.79

(2.94–4.23)*

3.00

(2.10–3.64)

3.21

(2.35–3.74)*

1.93

(0.97–2.43)

3.61

(2.92–4.50)

3.88

(3.22–4.59)

641

(457–858)^a

543

(438–960)

698

(481–862)

695

(457–819)

708

(578–943)

812

(646–1108)

509

(372–594)^b

320

(219–420)^a

331

(197–400)

330

(236–464)

252

(178–332)*

379

(296–559)

257

(173–381)

627

(429–928)^b

36.7

(28.3–49.0)^a

35.5

(26.9–58.8)

37.2

(28.8–49.0)

33.0

(22.0–49.0)

36.0

(30.9–42.5)

40.3

(32.9–58.6)

80.0

(60.5–105.0)^b

0.117

(0.097–0.149)^b

0.144

(0.095–0.152)*

0.116

(0.092–0.145)

0.142

(0.105–0.164)*

0.088

(0.076–0.114)

0.176

(0.156–0.197)

0.132

(0.104–0.149)^b

3967

(2556–7148)^a,b

2508

(1217–6053)*

4323

(3367–7358)

3446

(2611–4049)*

7323

(5432–9097)

1136

(547–3984)

1597

(1281–2781)

0.43

(0.21–1.25)

0.54

(0.29–1.45)*

0.41

(0.16–0.95)

0.45

(0.22–0.95)*

0.04

(0.04–0.33)

0.33

(0.04–1.36)

0.47

(0.19–1.43)