Table 3 Results of differential gene expression analysis in brain
From: Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer’s disease
RNA-Seq | Microarray | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
CER | TCX | CER | DLPFC | VCX | ||||||
Gene | β value (SE) | P value | β value (SE) | P value | β value (SE) | P value | β value (SE) | P value | β value (SE) | P value |
ECRG4 a | 0.06 (0.20) | 0.77 | 0.19 (0.24) | 0.43 | −0.18 (0.05) | 1.6 × 10 −3 | −0.12 (0.06) | 0.04 | −0.12 (0.04) | 2.7 × 10−3 |
HDAC9 | −0.24 (0.12) | 0.04 | −0.31 (0.08) | 1.5 × 10 −4 | −0.01 (0.02) | 0.77 | −0.09 (0.03) | 7.9 × 10−3 | −0.06 (0.02) | 5.6 × 10 −4 |
TRAPPC12 | −0.05 (0.06) | 0.35 | −0.13 (0.05) | 0.01 | −0.09 (0.03) | 1.1 × 10 −3 | −0.03 (0.02) | 0.09 | −0.08 (0.02) | 3.2 × 10 −4 |
TRAPPC12-AS1 | 0.22 (0.12) | 0.06 | 0.59 (0.18) | 1.3 × 10 −3 | – | – | – | – | – | – |
ADI1 | −0.10 (0.08) | 0.19 | −0.07 (0.08) | 0.36 | −0.10 (0.03) | 4.9 × 10 −4 | −0.03 (0.03) | 0.31 | −0.01 (0.03) | 0.64 |