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Table 1 Demographic characteristics and neuropsychiatric tests between the Bcl-2 A homozygotes and G carriers in Alzheimer’s disease

From: Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Group

G carriers (n = 76)

AA (n = 28)

p Value

Age, years

73.4 (7.6)

71.8 (7.4)

0.32

Education, years

5.7 (5.4)

5.4 (5.1)

0.4

Sex, male/female

42/34

11/17

0.186

ApoE ε4 allele-positive cases, n (%)

29 (38.5%)

13 (46.42%)

0.503

Use of rivastigmine/donepezil

37/39

17/11

0.377

Mini Mental State Examination score

21.6 (5.7)

20.6 (5.1)

0.286

CVVLT verbal memory (9)

 Trials 1–4 total

19.6 (7.08)

18.0 (6.9)

0.173

 30-second free recall

4.78 (2.6)

4.18 (2.73)

0.265

 10-minute free recall

3.52 (3.3)

3.21(2.8)

0.935

Visual memory

 Modified Rey-Osterrieth recall (17)

4.7 (5.2)

4.04 (4.16)

0.67

Visuospatial function

 Modified Rey-Osterrieth copy (17)

14.3 (5.0)

14.9 (4.6)

0.896

 Visual Object and Space Perception Battery (10)

6.4 (3.16)

5.8 (3.45)

0.446

Speech and language ability

 Semantic fluency: animal (1 minute)

11.2 (4.63)

10.33 (5.74)

0.387

 Boston Naming Test (15)

12.8 (3.0)

11.6 (2.8)

0.04a

 Comprehension (4)

2.8 (0.9)

2.3 (1.2)

0.053

Executive function

 Digit backward

3.2 (1.3)

3.2 (1.1)

0.758

 Stroop interference correct (1 minute)

25.9 (13.1)

21.6 (15.7)

0.178

 Design fluency

4.31 (2.8)

4.5 (3.8)

0.612

 Trail Making Test time (<120 seconds)

99.2 (32.3)

93.0 (37.9)

0.446

 Correct line in Trail Making Test (14)

7.1 (5.4)

7.6 (5.6)

0.742

  1. CVVLT Chinese Version Verbal Learning Test
  2. Data are presented as mean (SD); numbers in parentheses following task name are maximal scores
  3. ap < 0.05, Mann-Whitney U test