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Table 1 Demographic characteristics and neuropsychiatric tests between the Bcl-2 A homozygotes and G carriers in Alzheimer’s disease

From: Associations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease

Group G carriers (n = 76) AA (n = 28) p Value
Age, years 73.4 (7.6) 71.8 (7.4) 0.32
Education, years 5.7 (5.4) 5.4 (5.1) 0.4
Sex, male/female 42/34 11/17 0.186
ApoE ε4 allele-positive cases, n (%) 29 (38.5%) 13 (46.42%) 0.503
Use of rivastigmine/donepezil 37/39 17/11 0.377
Mini Mental State Examination score 21.6 (5.7) 20.6 (5.1) 0.286
CVVLT verbal memory (9)
 Trials 1–4 total 19.6 (7.08) 18.0 (6.9) 0.173
 30-second free recall 4.78 (2.6) 4.18 (2.73) 0.265
 10-minute free recall 3.52 (3.3) 3.21(2.8) 0.935
Visual memory
 Modified Rey-Osterrieth recall (17) 4.7 (5.2) 4.04 (4.16) 0.67
Visuospatial function
 Modified Rey-Osterrieth copy (17) 14.3 (5.0) 14.9 (4.6) 0.896
 Visual Object and Space Perception Battery (10) 6.4 (3.16) 5.8 (3.45) 0.446
Speech and language ability
 Semantic fluency: animal (1 minute) 11.2 (4.63) 10.33 (5.74) 0.387
 Boston Naming Test (15) 12.8 (3.0) 11.6 (2.8) 0.04a
 Comprehension (4) 2.8 (0.9) 2.3 (1.2) 0.053
Executive function
 Digit backward 3.2 (1.3) 3.2 (1.1) 0.758
 Stroop interference correct (1 minute) 25.9 (13.1) 21.6 (15.7) 0.178
 Design fluency 4.31 (2.8) 4.5 (3.8) 0.612
 Trail Making Test time (<120 seconds) 99.2 (32.3) 93.0 (37.9) 0.446
 Correct line in Trail Making Test (14) 7.1 (5.4) 7.6 (5.6) 0.742
  1. CVVLT Chinese Version Verbal Learning Test
  2. Data are presented as mean (SD); numbers in parentheses following task name are maximal scores
  3. ap < 0.05, Mann-Whitney U test