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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer’s disease

Fig. 2

Association of kallikrein 6 (KLK6) to apolipoprotein E (APOE) ε4 allele status, clinical diagnosis and core Alzheimer’s disease (AD) biomarker profile in cohort 1. a Box plot of plasma KLK6 in non-carriers (yellow box) and APOE ε4 carriers (orange box). b Box plot of cerebrospinal fluid (CSF) KLK6 in non-carriers (light blue box) and APOE ε4 carriers (dark blue box). c Bivariate plots showing linear correlations between plasma (upper panel) and CSF (lower panel) with Mini Mental State Examination (MMSE) scores, total tau (t-tau), phosphorylated tau (p-tau) and amyloid-β 1–42 (Aβ42). Clear dots = control subjects, red dots = patients with AD. NS Not significant

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