Fig. 2
Mean adjusted Z-scores for individual proteins in patients with stable MCI and patients with MCI-AD. Shown are box plots of the adjusted Z-scores for individual proteins per diagnostic group as results from the GEE analysis with all peptide clusters and the diagnosis × protein interaction. p Values were derived from the analyses stratified according to protein. *p < 0.05; **p < 0.01, ***p < 0.001. β 2 M β2-Microglobulin, CHGA Chromogranin A, CysC Cystatin C, LysC Lysozyme C, MCI Mild cognitive impairment, MCI-AD Mild cognitive impairment progressing to Alzheimer’s disease dementia, NCANP Neurocan core protein, NFASC Neurofascin, NPTX1 Neuronal pentraxin 1, NRXN Neurexin, SCG2 Secretogranin 2, VGF Neurosecretory protein VGF