Fig. 5

Transactive response DNA-binding protein pathology in different brain areas. ± (sparse (0–1/mm²)), + (mild (< 5/mm²)), ++ (moderate (5–20/mm²)), +++ (extensive (> 20/mm)). The average lesion load is shown for the most important regions of interest. Striped bar represents the amount of neuronal intracytoplasmic inclusions, whereas the dark bar represents the amount of short dystrophic neurites. With the dotted bar, the neuronal intranuclear inclusions are shown. NCI Neuronal intracytoplasmic inclusions, DN Dystrophic neurites, NII Nuclear intraneuronal inclusions, DMF Dorsomedial formation, ER Entorhinal cortex, TER Transentorhinal cortex, GOTL Gyrus occipitotemporalis lateralis, DG Dentate gyrus