Fig. 2

Regional binding distribution in brain homogenate. Regional binding distribution of 3H-THK5117 and 3H-THK5351 in postmortem frontal cortex, temporal cortex, and hippocampus tissue from three patients with Alzheimer’s disease and three control subjects. Error bars represent the SEM from three experiments in triplicate. Two-way analysis of variance multiple comparisons with Prism software was performed. * p < 0.05, ** p < 0.005, # p < 0.0001. AD Alzheimer’s disease, FC Frontal cortex, Hip Hippocampus, TC Temporal cortex