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Table 4 Association between anemia and new cognitive decline after 4-year follow-up among individuals with normal cognitive function at baseline (n = 8988)

From: Anemia is associated with incidence of dementia: a national health screening study in Korea involving 37,900 persons

 

Unadjusted OR (95% CI)

aORa (95% CI)

Anemiab

1.32 (1.09–1.60)

1.30 (1.03–1.62)

Female sex

 

1.73 (1.39–2.16)

BMI, kg/m2

  < 18.5

 

0.86 (0.47–1.56)

 18.5–24.9

 

1.00

  ≥ 25

 

1.04 (0.88–1.23)

Smoking status

 Never

 

1.00

 Former

 

1.29 (0.97–1.71)

 Current

 

1.37 (1.02–1.83)

Household income status percentiles

  ≤ 20 (low)

 

1.00

 30–50

 

1.18 (0.91–1.53)

 60–80

 

1.17 (0.91–1.49)

  ≥ 90 (high)

 

1.12 (0.87–1.44)

Disability

 

2.88 (0.62–13.30)

Depressive symptoms

 

1.33 (1.11–1.60)

Hypertension

 

0.98 (0.82–1.17)

Diabetes

 

0.98 (0.78–1.23)

Dyslipidemia

 

0.92 (0.73–1.16)

  1. aOR Adjusted odds ratio, BMI Body mass index
  2. aAdjusted for sex, baseline Prescreening Korean Dementia Screening Questionnaire score, BMI, smoking status, household income, disability, depressive symptoms, hypertension, diabetes, and dyslipidemia
  3. bAccording to World Health Organization anemia criteria, anemia was defined as hemoglobin < 13 g/dl for men and < 12 g/dl for women