Table 5 Estimated odds ratios for each scenario based on the proportional odds model
From: Attitudes toward clinical trials across the Alzheimer’s disease spectrum
Covariate | Low risk, low burden | Medium risk, medium burden | High risk, high burden | |||
|---|---|---|---|---|---|---|
Estimated OR (95% CI) | P value | Estimated OR (95% CI) | P value | Estimated OR (95% CI) | P value | |
Diagnosis | ||||||
Dementia | 1.0 | 1.0 | 1.0 | |||
MCI | 0.88 (0.23–3.29) | 0.844 | 0.64 (0.17–2.40) | 0.507 | 0.27 (0.06–1.15) | 0.076 |
CN | 0.30 (0.08–1.09) | 0.067 | 0.21 (0.06–0.77) | 0.019 | 0.12 (0.03–0.54) | 0.006 |
Partner involvement | ||||||
Some help | 0.65 (0.22–1.96) | 0.448 | 1.12 (0.38–3.30) | 0.834 | 0.58 (0.16–2.11) | 0.408 |
Marital status | ||||||
Married (living as) | 3.06 (1.12–8.35) | 0.029 | 2.26 (0.82–6.22) | 0.114 | 1.84 (0.63–5.41) | 0.266 |
Gender | ||||||
Female | 2.04 (0.84–4.97) | 0.117 | 1.99 (0.80–4.95) | 0.139 | 2.64 (0.97–7.17) | 0.056 |
Age (5 years) | 1.30 (1.04–1.62) | 0.021 | 1.21 (0.96–1.51) | 0.102 | 1.14 (0.90–1.45) | 0.276 |
Education | 0.78 (0.65–0.93) | 0.007 | 0.77 (0.64–0.93) | 0.007 | 0.80 (0.65–0.97) | 0.024 |