Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13195-017-0309-z/MediaObjects/13195_2017_309_Fig4_HTML.gif)
Fluorescent immunostaining in sporadic Alzheimer’s disease cases. Confocal microscopy using IC16 (red), 029-2 (green), and 4′,6-diamidino-2-phenylindole (DAPI; blue) reveals colocalization of IC16 and 029-2 staining in cored but not diffuse amyloid deposits (a). In blood vessels, partially overlapping staining profiles were observed; however, distinct immunoreactivity of IC16 and 029-2 also was evident within the vessel wall (b, arrowheads). Scale bar = 33 μm (a); 15 μm (b)