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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

Fig. 4

Fluorescent immunostaining in sporadic Alzheimer’s disease cases. Confocal microscopy using IC16 (red), 029-2 (green), and 4′,6-diamidino-2-phenylindole (DAPI; blue) reveals colocalization of IC16 and 029-2 staining in cored but not diffuse amyloid deposits (a). In blood vessels, partially overlapping staining profiles were observed; however, distinct immunoreactivity of IC16 and 029-2 also was evident within the vessel wall (b, arrowheads). Scale bar = 33 μm (a); 15 μm (b)

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