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Table 4 P values showing pairwise statistical comparisons of single predictor receiver operating characteristic curves based on area under the curve

From: Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia

  HCV Aβ42 Aβ40 p-Tau t-Tau MMSE CDR-sb CERAD-DR Aβ42/Aβ40
HCV   ns 0.03 ns ns ns ns ns ns
Aβ42    ns ns ns ns ns ns ns
Aβ40     0.02 0.00 0.04 0.02 0.05 0.06
p-Tau      0.03 ns ns ns ns
t-Tau       ns ns ns 0.02
MMSE        ns ns ns
CDR-sb         ns ns
CERAD-DR          ns
  1. Significant values are shown in bold typeface
  2. Data were not corrected for multiple testing
  3. For comparing areas under the curve we used a bootstrapping algorithm as implemented in pROC packages (Version 1.8)
  4. Aβ40 amyloid-beta1–40, Aβ42 amyloid-beta1–42, CDR-sb Clinical Dementia Rating–sum-of-boxes, CERAD-DR Consortium to Establish a Registry of Dementia–delayed recall, HCV hippocampal volume, MMSE Mini-Mental State Examination, ns not significant, p-Tau phosphorylated tau, t-Tau total tau