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Table 2 Liver fatty acid composition in mice fed oleic acid-enriched or arachidonic acid-enriched diet (%)

From: Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance

  OLE ARA
Palmitic acid (16:0) 26.49 ± 0.56 24.55 ± 0.36a
Stearic acid (18:0) 13.48 ± 0.39 16.73 ± 0.74b
Palmitoleic acid (16:1) 1.25 ± 0.08 0.94 ± 0.06a
Oleic acid (18:1) 16.08 ± 1.53 10.09 ± 0.56b
Linoleic acid (18:2 ω-6) 15.38 ± 0,87 12.86 ± 0.81c
Arachidonic acid (20:4 ω-6) 15.97 ± 0.61 27.46 ± 0.77b
Docosatetraenoic acid (22:4 ω-6) 0.47 ± 0.01 1.93 ± 0.16b
α-Linolenic acid (18:3 ω-3) 0.41 ± 0.04 0.52 ± 0.05
Eicosapentaenoic acid (20:5 ω-3) 0.48 ± 0.06 0.06 ± 0.01b
Docosahexaenoic acid (22:6 ω-3) 10.00 ± 0.27 6.10 ± 0.26b
 Sum of ω-6 PUFA 31.8 42.25
 Sum of ω-3 PUFA 10.89 6.69
  1. ARA Arachidonic acid-enriched diet, OLE Oleic acid-enriched diet, PUFA Polyunsaturated fatty acid
  2. a p < 0.01, ARA compared with OLE. n = 10 in each diet group (OLE or ARA)
  3. b p < 0.001, ARA compared with OLE. n = 10 in each diet group (OLE or ARA)
  4. c p < 0.05, ARA compared with OLE. n = 10 in each diet group (OLE or ARA)
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Alzheimer's Research & Therapy

ISSN: 1758-9193