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Table 3 Baseline characteristics of the MEMENTO cohort

From: Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort

  Total
No. of subjects 2323
Female sex, % 61.8
Age in years, mean (SD) 70.9 (8.7)
Baccalaureate degree or higher education level, % 54.8
Diabetes, % 7.4
Hypertension, % 33.8
Dyslipidaemia, % 27.8
History of cardiovascular disease, % 11.8
Apathy, % 17.2
Depression,% 33.6
Anxiety, % 41.8
No. of limitations in IADL, %
 One 10.3
 Two or more 2.6
SPPB score, mean (SD) 10.6 (1.9)
At least one APOE ε4 allele for carried, % 30.0
CDR Sum of Boxes, mean (SD) 0.6 (0.7)
MMSE score, mean (SD) 27.9 (1.9)
Verbal fluency, letter P, mean (SD) 20.4 (7.2)
Verbal fluency, animals, mean (SD) 28.3 (8.8)
DMS48, immediate recall, mean (SD) 44.7 (4.0)
Praxis total score, mean (SD) 21.8 (1.6)
TMT A, time in seconds, mean (SD) 2.1 (0.93)
TMT B, time in seconds, mean (SD) 5.2 (4.4)
FCSRT total immediate free recall, mean (SD) 25.9 (8.4)
FCSRT total free and cued delayed recall, mean (SD) 14.9 (2.3)
Digit span standardised score, mean (SD) 9.9 (3.1)
Rey Complex Figure Test, immediate copy score, mean (SD) 32.9 (4.3)
Rey Complex Figure Test, 3-minute copy score, mean (SD) 15.1 (7.0)
FAB score, mean (SD) 16.2 (1.9)
DO 80 score, mean (SD) 78.6 (3.3)
Hippocampal volume, right, cm3, mean (SD) 2.76 (0.42)
Hippocampal volume, left, cm3, mean (SD) 2.66 (0.41)
Brain parenchymal fraction, %, mean (SD) 81.5 (1.3)
White matter lesion volume, cm3, mean (SD) 10.3 (13.8)
Cortical thickness, right, mm, mean (SD) 2.32 (0.11)
Cortical thickness left, mm, mean (SD) 2.33 (0.11)
Angular and parietal inferior, right, FDG uptake, mean (SD) 1.74 (0.21)
Parietal inferior, left, FDG uptake, mean (SD) 1.71 (0.21)
Precuneus and cingulum, posterior left, FDG uptake, mean (SD) 1.94 (0.24)
Temporal, inferior left, FDG uptake, mean (SD) 1.62 (0.17)
Temporal, inferior right, FDG uptake, mean (SD) 1.64 (0.17)
  1. Abbreviations: APOE Apolipoprotein E, CDR Clinical Dementia Rating, DO 80 Dénomination Orale D’images, DMS48 Delayed Matching to Sample 48, FAB Frontal Assessment Battery, FCSRT Free and Cued Selective Reminding Test, FDG 18F-fluorodeoxyglucose, IADL Instrumental Activities of Daily Living, MMSE Mini Mental State Examination, SPPB Short Physical Performance Battery, TMT Trail Making Test