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Table 1 Demographic characteristics of the study cohort at baseline

From: Association between chronic periodontitis and the risk of Alzheimer’s disease: a retrospective, population-based, matched-cohort study

Variable Total Chronic periodontitis p value
    With Without  
  n % n % n %  
Total 27,963 100 9291 100 18,672 100  
Sex
 Female 13,119 46.92 4351 46.83 8768 46.96 0.8402
 Male 14,844 53.08 4940 53.17 9904 53.04  
Age, years
 50–59 13,947 49.88 4638 49.92 9309 49.86 0.9705
 60–69 8853 31.66 2945 31.70 5908 31.64  
 ≥70 5163 18.46 1708 18.38 3455 18.50  
Hypertension
 No 6654 23.80 2251 24.23 4403 23.58 0.2314
 Yes 21,309 76.20 7040 75.77 14,269 76.42  
Hyperlipidaemia
 No 21,651 77.43 6935 74.64 14,716 78.81 <0.0001
 Yes 6312 22.57 2356 25.36 3956 21.19  
Chronic kidney disease
 No 17,243 61.66 5697 61.32 11,546 61.84 0.4009
 Yes 10,720 38.34 3594 38.68 7126 38.16  
Depression
 No 23,283 83.26 7619 82.00 15,664 83.89 <0.0001
 Yes 4680 16.74 1672 18.00 3008 16.11  
Stroke
 No 21,316 76.23 7081 76.21 14,235 76.24 0.9652
 Yes 6647 23.77 2210 23.79 4437 23.76  
Diabetes mellitus
 No 14,545 52.02 4627 49.8 9918 53.12 <0.0001
 Yes 13,418 47.98 4664 50.2 8754 46.88  
Traumatic brain injury
 No 22,517 80.52 7562 81.39 14,955 80.09 0.0099
 Yes 5446 19.48 1729 18.61 3717 19.91  
CCI score
 0 17,032 60.91 6423 69.13 10,609 56.82 <0.0001
 1 7826 27.99 2206 23.74 5620 30.10  
 2 3105 11.10 662 7.13 2443 13.08  
 ≥3 1685 6.03 499 5.37 1186 6.35  
Urbanisation level
 1 2896 10.36 890 9.58 2006 10.74 <0.0001
 2 3675 13.14 1219 13.12 2456 13.15  
 3 19,707 70.48 6683 71.93 13,024 69.75  
  1. CCI Charlson comorbidity index