Fig. 2

Effect of the addition of 0.05% detergent to the BIOTIN component (= biotinylated antibody) on calibration curves and samples in the neurogranin trunc P75, α-synuclein, and total tau. A representative calibration curve is presented. Each calibrator point is the mean of duplicate optical density (OD) values. Horizontal lines represent the mean OD values derived from all cerebrospinal fluid (CSF) samples as a function of the relevant collection protocol