Table 2 Prevalence of antipsychotic prescribing and concomitant psychotropic medications across years from 2010 to 2014
2010 | 2011 | 2012 | 2013 | 2014 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | ||
At least one antipsychotic prescribing | |||||||||||
Overall | No | 43,742 | (93.5) | 55,898 | (92.9) | 63,758 | (92.9) | 68,369 | (92.7) | 71,853 | (92.3) |
Yes | 3,039 | (6.5) | 4,301 | (7.1) | 4,907 | (7.2) | 5,400 | (7.3) | 6,013 | (7.7) | |
Total | 46,781 | 60,199 | 68,665 | 73,769 | 77,866 | ||||||
Alzheimer’s disease | No | 30,123 | (93.4) | 38,513 | (92.9) | 43,454 | (93.0) | 45,857 | (92.8) | 47,180 | (92.4) |
Yes | 2,146 | (6.7) | 2,954 | (7.1) | 3,276 | (7.0) | 3,549 | (7.2) | 3,871 | (7.6) | |
Total | 32,269 | 41,467 | 46,730 | 49,406 | 51,051 | ||||||
Mixed dementia | No | 10,011 | (93.8) | 12,669 | (92.6) | 14,599 | (92.5) | 15,928 | (92.5) | 17,208 | (92.0) |
Yes | 661 | (6.2) | 1,006 | (7.4) | 1,184 | (7.5) | 1,299 | (7.5) | 1,491 | (8.0) | |
Total | 10,672 | 13,675 | 15,783 | 17,227 | 18,699 | ||||||
Vascular dementia | No | 3,608 | (94.0) | 4,716 | (93.3) | 5,705 | (92.7) | 6,584 | (92.3) | 7,465 | (92.0) |
Yes | 232 | (6.0) | 341 | (6.7) | 447 | (7.3) | 552 | (7.7) | 651 | (8.0) | |
Total | 3,840 | 5,057 | 6,152 | 7,136 | 8,116 | ||||||
Psychotropic associations among patients receiving at least one antipsychotic prescribing | |||||||||||
Antipsychotic only | 1,002 | (33.0) | 1,248 | (29.0) | 1,471 | (30.0) | 1,676 | (31.0) | 1,722 | (28.6) | |
Antipsychotic + hypnotic | 153 | (5.0) | 174 | (4.1) | 217 | (4.4) | 215 | (4.0) | 205 | (3.4) | |
Antipsychotic + hypnotic + antidepressant | 134 | (4.4) | 208 | (4.8) | 192 | (3.9) | 215 | (4.0) | 228 | (3.8) | |
Antipsychotic + antidepressant | 639 | (21.0) | 976 | (22.7) | 1,07 | (21.8) | 1,142 | (21.2) | 1,285 | (21.4) | |
Antipsychotic + anxiolytic | 377 | (12.4) | 531 | (12.4) | 619 | (12.6) | 680 | (12.6) | 739 | (12.3) | |
Antipsychotic + anxiolytic + hypnotic | 106 | (3.5) | 125 | (2.9) | 148 | (3.0) | 172 | (3.2) | 202 | (3.4) | |
Antipsychotic + anxiolytic + antidepressant | 463 | (15.2) | 767 | (17.8) | 895 | (18.2) | 982 | (18.2) | 1,222 | (20.3) | |
Antipsychotic + anxiolytic + hypnotic + antidepressant | 165 | (5.4) | 272 | (6.3) | 295 | (6.0) | 318 | (5.9) | 410 | (6.8) | |
Anti-dementia agents among patients receiving at least one antipsychotic prescribing | |||||||||||
NMDA antagonist | No | 1,756 | (57.8) | 2,865 | (66.6) | 3,556 | (72.5) | 3,981 | (73.7) | 3,933 | (65.4) |
Yes | 1,283 | (42.2) | 1,436 | (33.4) | 1,351 | (27.5) | 1,419 | (26.3) | 2,080 | (34.6) | |
ChEI | No | 1,433 | (47.2) | 1,981 | (46.1) | 2,588 | (52.7) | 3,323 | (61.5) | 3,443 | (57.3) |
Yes | 1,606 | (52.9) | 2,320 | (53.9) | 2,319 | (47.3) | 2,077 | (38.5) | 2,570 | (42.7) | |
ChEI + NMDA antagonist | No | 2,473 | (81.4) | 3,616 | 84.1 | 4,345 | (88.6) | 4,946 | (91.6) | 5,227 | (86.9) |
Yes | 566 | (18.6) | 685 | 15.9 | 562 | (11.4) | 454 | (8.4) | 786 | (13.1) | |
Total | 3,039 | 4,301 | 4,907 | 5,400 | 6,013 | ||||||