Fig. 4
From: Memory is preserved in older adults taking AT1 receptor blockers
White matter hyperintensity (WMH) volume over the 3-year follow-up period. a estimated marginal means after correction for demographics only, b means adjusted for demographics and Alzheimer’s Disease Neuroimaging Initiative site. After all corrections, the participants who took other antihypertensive drugs that were not angiotensin II receptor blockers (HTN-Other) showed significantly greater WMH volume over time compared with users of blood-brain barrier (BBB)-crossing angiotensin II receptor blocker users (ARBs; BBB crossers) and normotensive subjects. Within the ARB users, the BBB crossers group had less WMH volume than users of non-BBB-crossing ARBs