Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer’s disease

Table 1 Mean scores of neuropsychological tests at inclusion of study and follow-up, as well as changes (%) in performance between sessions

Test	Inclusion	Follow-up	p value^*	Total sample (n = 37), % change per year	No decline, % change per year	No decline p value^*	Decline, % change per year	Decline p value^*
MMSE	29.03 (1.17)	29.03 (1.19)	1.00	0.00	1.83% (n = 23)	<0.001	–1.97% (n = 14)	<0.0001
BNT	14.32 (1)	14.46 (0.84)	0.53	0.01	1.45% (n = 33)	<0.01	–5.53% (n = 4)	<0.015
DSF	6.81 (1.66)	6.84 (1.55)	0.94	0.02	10.32% (n = 24)	<0.01	–14.09% (n = 13)	<0.001
DSB	6.08 (1.57)	5.95 (1.73)	0.73	0.00	10.32% (n = 20)	<0.001	–11.69% (n = 17)	<0.0001
TMT B/A	2.83 (1.27)	2.61 (1)	0.41	0.00	17.51% (n = 19)	<0.002	–18.84% (n = 18)	<0.001
VLMT delayed recall	8.49 (3.92)	9.62 (4.21)	0.23	0.19	46.22% (n = 19)	<0.001	–9.31% (n = 18)	<0.01

Values are shown as mean (SD)
^*Follow-up versus inclusion
BNT Boston Naming Test, DSB Digit Span Backward, DSF Digit Span Forward, MMSE Mini-Mental State Examination, TMT B/A Trail Making Test part B/part A, VLMT Verbal Learning and Memory Test

ISSN: 1758-9193