Predicting dementia using socio-demographic characteristics and the Free and Cued Selective Reminding Test in the general population

Table 3 AUC comparisons between the cross-validated risk scores^a and the FCSRT crude scores for the prediction of dementia and Alzheimer's disease at 3 and 5 years in the Montpellier center (testing dataset)

	Dementia at 3 years		Dementia between 3 and 5 years		Dementia at 5 years		AD at 3 years		AD between 3 and 5 years		AD at 5 years
	AUC (CI)	p value	AUC (CI)	p value	AUC (CI)	p value	AUC (CI)	p value	AUC (CI)	p value	AUC (CI)	p value
FCSRT free recall
Crude score	0.89 (0.80–0.99)	0.44	0.87 (0.79–0.95)	0.80	0.89 (0.83–0.95)	0.84	0.92 (0.82–1.00)	0.79	0.85 (0.74–0.95)	0.92	0.88 (0.81–0.96)	0.34
Risk score	0.89 (0.79–0.98)		0.82 (0.73–0.91)		0.89 (0.83–0.95)		0.92 (0.81–1.00)		0.84 (0.74–0.95)		0.89 (0.82–0.97)
FCSRT total recall
Crude score	0.89 (0.79–0.98)	0.11	0.80 (0.70–0.89)	0.93	0.84 (0.77–0.91)	0.82	0.91 (0.80–1.00)	0.18	0.79 (0.67–0.91)	0.42	0.84 (0.75–0.93)	0.95
Risk score	0.86 (0.75–0.96)		0.76 (0.66–0.86)		0.83 (0.76–0.90)		0.88 (0.76–1.00)		0.76 (0.64–0.88)		0.84 (0.75–0.93)
FCSRT delayed free recall
Crude score	0.86 (0.76–0.97)	0.91	0.81 (0.71–0.90)	0.53	0.83 (0.77–0.90)	0.27	0.92 (0.82–1.00)	0.94	0.78 (0.66–0.90)	0.66	0.84 (0.76–0.93)	0.04
Risk score	0.86 (0.76–0.96)		0.75 (0.65–0.85)		0.85 (0.78–0.91)		0.92 (0.82–1.00)		0.77 (0.65–0.90)		0.86 (0.78–0.94)
FCSRT delayed total recall
Crude score	0.86 (0.75–0.96)	0.11	0.71 (0.60–0.82)	0.33	0.77 (0.69–0.85)	0.64	0.88 (0.75–1.00)	0.00	0.69 (0.56–0.82)	0.22	0.77 (0.67–0.86)	0.35
Risk score	0.72 (0.59–0.85)		0.73 (0.63–0.83)		0.79 (0.71–0.86)		0.69 (0.53–0.85)		0.75 (0.63–0.88)		0.81 (0.72–0.90)

^aThe cross-validated risk scores were constructed using the Bordeaux data (training dataset)
AUC area under the curve, CI confidence interval. FCSRT Free and Cued Selective Reminding Test

ISSN: 1758-9193