Skip to main content
Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Identifying biomarkers of dementia prevalent among amnestic mild cognitively impaired ethnic female patients

Fig. 1

Plasma biomarkers revealing significant association with the incidence of aMCI in ethnic cohorts. a40 levels were significantly increased in White (p = 0.0001, 95 % CI: 58.0–134.0) and Hispanic (p < 0.01, 95 % CI: 66.8–142.8) aMCI patients compared with their respective age-matched control group (NC). b Plasma Aβ42 levels were significantly increased in the Hispanic aMCI patient population (p < 0.005, 95 % CI: 15.5–31.8) compared with the NC group. c42/Aβ40 ratio displayed no significant changes among aMCI ethnic groups. d YKL-40 levels were significantly increased in the aMCI group of the Hispanic population compared with its NC group (p < 0.05, 95 % CI: 10.7–97.7). e Plasma total tau levels were significantly associated with aMCI incidence in the African American aMCI patient cohort (p < 0.05, 95 % CI: 0.06–0.15), while f plasma phospho-tau levels remained unchanged independent of ethnicity and disease progression. g Plasma cystatin C levels in the Hispanic patient cohorts are associated with the incidence of aMCI (p < 0.05, 95 % CI: 844.8–1240.7). Statistical analyses were performed in a two by three factorial design with post-hoc analyses using IBM SPSS Statistics 22. An outlier test via IBM SPSS Statistics 22 was performed on each data set and outliers were removed. aMCI amnestic mild cognitive impairment

Back to article page