Fig. 2

Cortical regions of interest where PET tracer retention was significantly associated with cognition in AD patients, after adjusting for delay (not corrected for multiple comparisons). Linear models assessed the association between cognitive performance using five different tests (each row) and (a). [¹⁸F]THK5317 retention (DVR) or (b). [¹⁸F]FDG uptake (SUVR). Regions are defined according to the Harvard-Oxford atlas. T-values for significant negative associations are displayed with a blue color scale and T-values for significant positive associations are displayed with a red color scale. FSIQ full-scale intelligence quotient, MMSE mini mental state examination, RAVL Rey auditory verbal learning test, Rey Rey-Osterrieth complex figure test