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Table 1 Demographic and clinical data of participants

From: Brain perfusion in dementia with Lewy bodies and Alzheimer’s disease: an arterial spin labeling MRI study on prodromal and mild dementia stages

Characteristic

Pro DLB

Mild DLB

Pro AD

Mild AD

HC

Participants

46

16

13

25

21

Female

26

8

4 a

17

12

Age, years (SD)

69.4 (8.8)

74.7 (10.2)

74.5 (9.9)

73.6 (9.1)

64.8 (8.6)

MMSE score (SD) (maximum 30)

27.5 (1.4)

20.7 (3.4)

27.1 (1.5)

19.5 (3.4)

28.9 (1.0)

Participants with visual hallucinations

19

9

0

3

0

Participants with parkinsonism

34

11

1

7

0

Participants with cognitive fluctuations

28

9

0

5

0

Medial temporal lobe atrophy (L, R)

 

Participants with a score of 0

18, 16

6, 4

3, 3

7, 5

13, 9

Participants with a score of 1

11, 12

1, 4

5, 6

5, 9

7, 10

Participants with a score of 2

12, 15

4, 4

4, 4

7, 5

1, 2

Participants with a score of 3

5, 2

3, 2

1, 0

5, 3

0, 0

Participants with a score of 4

0, 1

2, 2

0, 0

1, 3

0, 0

Parietal lobe atrophy (L, R)

 

Participants with a score of 0

14, 14

9, 8

4, 2

5, 6

7, 8

Participants with a score of 1

16, 17

4, 5

7, 8

8, 6

9, 8

Participants with a score of 2

12, 11

3, 3

2, 3

9, 9

4, 5

Participants with a score of 3

0, 4

4, 0

0, 0

3, 4

0, 0

Participants with a score of 4

0, 0

0, 0

0, 0

0, 0

0, 0

Vascular damage in white matter

 

Participants with a score of 0

25

4

7

9

7

Participants with a score of 1

15

7

4

7

12

Participants with a score of 2

6

4

1

7

2

Participants with a score of 3

0

1

1

2

0

Vascular damage in basal ganglia

 

Participants with a score of 0

33

13

10

17

21

Participants with a score of 1

11

1

2

5

0

Participants with a score of 2

2

1

1

0

0

Participants with a score of 3

0

1

0

3

0

Participants with AchI medication

14

11

2

17

0

Participants with dopaminergic medication

13

6

0

0

0

  1. Medial temporal lobe atrophy, parietal lobe atrophy, and vascular damage were assessed according to the Scheltens, Koedam, and Wahlund scales, respectively. Pro AD were more male than mild AD. Mild DLB, pro AD, and mild AD were older than HC AchI acetylcholinesterase inhibitor, AD Alzheimer’s disease, DLB dementia with Lewy bodies, HC healthy (elderly) controls, L left hemisphere, MMSE Mini-Mental State Examination, R right hemisphere, SD standard deviation
  2. *p < 0.05
  3. ap < 0.01