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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer’s disease

Fig. 2

Baseline plasma phospholipid and CSF DHA levels by CSF Aβ42 tertiles. Baseline phospholipid and CSF DHA measurements were compared in three groups of participants based on CSF Aβ42 tertiles at baseline (n = 44, T1 = Aβ42 levels <147 pg/ml, T2 = Aβ42 levels between 147 and 174 pg/ml, and T3 = Aβ42 levels >174 pg/ml). The ratio of CSF to plasma DHA was calculated as an index of DHA transport across the blood-brain barrier (a and b). There was no significant difference in plasma phospholipid of CSF DHA by Aβ42 tertiles at baseline. c A trend was observed for lower baseline CSF to plasma DHA (p = 0.15 for three-way group comparison, p = 0.19 for difference between T1 and T2, and p = 0.06 for difference between T1 and T3) in the lowest tertile of Aβ42. Aβ42 amyloid-β42, CSF cerebrospinal fluid, DHA docosahexaenoic acid

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