Exploring anterograde memory: a volumetric MRI study in patients with mild cognitive impairment

Table 5 GM volume regions positively correlated with the score on the DMS-48 for the whole group of patients (group ABC) using VBM

Group (score)	P	Brain region	Side	BA	k	x	y	z	T
ABC (Set1), n = 138	P = 0.001	Hippocampus	R	NA	606/1377	27	–34	–1	4.31
		Parahippocampal g.	R	28, 35–37	557/1377	28	–39	–6	4.36
		Hippocampus	L	NA	67/264	–28	–40	0	3.47
		Parahippocampal g.		19, 31	38/264	–27	–45	–10	3.41
		Precuneus		31	70/70	–2	–71	21	3.43
ABC (Set2), n = 138	P _FWE = 0.05	Hippocampus	R	NA	370	28	–37	–3	5.42
	P _FWE = 0.05	Parahippocampal g.	R	36–37	370	27	–37	–9	5.33
	P = 0.001	Hippocampus	R	NA	1303/3820	30	–25	–12	4.65
		Parahippocampal g.	R	19, 28, 35–37	834/3820	22	–19	–22	4.02
		Hippocampus	L	NA	94/279	–25	–39	–3	3.67

Statistical analyses were performed including age, gender, education level, total GM volume and centre as nuisance covariate, with a threshold of P = 0.05, FWE or P = 0.001, uncorrected, including a minimal k of 50 voxels
GM grey matter, DMS-48, Delayed Matching-to-Sample—48 items, VBM voxel-based morphometry, L left, R right, BA Brodmann area, k cluster size in voxel (specific region’s volume/cluster’s global volume), x, y, z Talairach coordinates, T T value, g. gyrus, FWE family-wise error, Set1 immediate score, Set2 1-hour delayed score

ISSN: 1758-9193