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Table 5 GM volume regions positively correlated with the score on the DMS-48 for the whole group of patients (group ABC) using VBM

From: Exploring anterograde memory: a volumetric MRI study in patients with mild cognitive impairment

Group (score) P Brain region Side BA k x y z T
ABC (Set1), n = 138 P = 0.001 Hippocampus R NA 606/1377 27 –34 –1 4.31
Parahippocampal g. 28, 35–37 557/1377 28 –39 –6 4.36
Hippocampus L NA 67/264 –28 –40 0 3.47
Parahippocampal g. 19, 31 38/264 –27 –45 –10 3.41
Precuneus 31 70/70 –2 –71 21 3.43
ABC (Set2), n = 138 P FWE = 0.05 Hippocampus R NA 370 28 –37 –3 5.42
Parahippocampal g. 36–37 370 27 –37 –9 5.33
P = 0.001 Hippocampus R NA 1303/3820 30 –25 –12 4.65
Parahippocampal g. 19, 28, 35–37 834/3820 22 –19 –22 4.02
Hippocampus L NA 94/279 –25 –39 –3 3.67
  1. Statistical analyses were performed including age, gender, education level, total GM volume and centre as nuisance covariate, with a threshold of P = 0.05, FWE or P = 0.001, uncorrected, including a minimal k of 50 voxels
  2. GM grey matter, DMS-48, Delayed Matching-to-Sample—48 items, VBM voxel-based morphometry, L left, R right, BA Brodmann area, k cluster size in voxel (specific region’s volume/cluster’s global volume), x, y, z Talairach coordinates, T T value, g. gyrus, FWE family-wise error, Set1 immediate score, Set2 1-hour delayed score