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Table 3 Factors associated with the lamina cribrosa thickness

From: Increased CSF tau level is correlated with decreased lamina cribrosa thickness

  Univariate analysis Multivariate analysis VIF
β 95 % CI P value β 95 % CI P value
Gender, male 5.769 –15.954, 27.493 0.595     
Age, per 1 year older –1.103 –2.371, 0.165 0.087 –0.572 –1.746, 0.601 0.330 1.086
1–42, per 1 pg/ml larger –0.024 –0.100, 0.052 0.521     
T-tau, per 1 pg/ml larger –0.326 –0.543, –0.108 0.004 –0.362 –0.709, –0.016 0.041 2.843
P-tau181P , per 1 pg/ml larger –0.582 –1.095, –0.069 0.027 0.166 –0.627, 0.958 0.674 2.882
CSF pressure, per 1 mmHg higher 0.593 –3.526, 4.712 0.773     
Total MMSE score, per 1 point higher 0.894 –1.108, 2.896 0.373     
IOP, per 1 mmHg higher 0.294 –3.737, 4.325 0.884     
Spherical error, per 1 D larger 0.024 –5.983, 6.032 0.994     
Global RNFL thickness, per 1 μm thicker 0.930 –0.025, 1.886 0.056 0.845 –0.020, 1.709 0.055 1.113
Central corneal thickness, per 1 μm thicker 0.349 0.032, 0.666 0.032 0.216 –0.091, 0.524 0.163 1.145
Axial length, per 1 mm longer 3.516 –7.861, 14.893 0.536     
  1. Statistically significant values are shown in bold
  2. 1–42 amyloid β1–42, CI confidence interval, CSF cerebrospinal fluid, IOP intraocular pressure, MMSE Mini-Mental Status Examination, P-tau 181P phosphorylated tau181P, RNFL retinal nerve fiber layer, T-tau total tau, VIF variance inflation factor