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Table 1 Subjects’ clinical characteristics

From: Increased CSF tau level is correlated with decreased lamina cribrosa thickness

  AD group (n = 18) Healthy group (n = 26) P value
Gender (male:female)a 7:11 12:14 0.760
Age (years)b 69.7 ± 7.6 63.4 ± 8.0 0.012
Baseline IOP (mmHg)c 11.5 ± 2.8 12.9 ± 2.5 0.262
SE (D)c 0.1 ± 2.2 0.7 ± 1.6 0.567
Central corneal thickness (μm)b 559.6 ± 30.4 572.1 ± 33.6 0.207
Axial length (mm)b 23.6 ± 1.0 23.8 ± 1.0 0.519
RNFL thickness (μm)b 102.7 ± 12.1 100.0 ± 12.3 0.474
Total MMSE scorec 19.5 ± 3.7 29.0 ± 1.3 <0.001
BMI (kg/m2)b 23.9 ± 3.3 23.8 ± 2.4 0.957
Presence of diabetes mellitusa 3 (16.7 %) 5 (19.2 %) 1.000
Presence of systemic hypertensiona 10 (55.6 %) 9 (34.6 %) 0.222
  1. Data are presented as the mean ± standard deviation unless otherwise specified. Statistically significant values are shown in bold
  2. aComparisons were made using Fisher’s exact test
  3. bComparisons were made using an independent-samples t test
  4. cComparisons were made using a Mann–Whitney U test
  5. AD Alzheimer’s disease, BMI Body mass index, IOP intraocular pressure, MMSE Mini-Mental Status Examination, RNFL retinal nerve fiber layer, SE spherical equivalent