|
Reaction Time (RTI)
|
|---|
|
Drug
|
Name of task
|
Mean ± SEM
|
p1 value
|
95 % CI-D (Lower, Upper)
|
Cohen’s d for p1 Value
|
p2 Value
|
95 % CI-D (Lower, Upper)
|
Cohen’s d for p2 Value
|
|---|
|
Baseline
|
After 7 Days
|
|---|
|
OME
|
RTI FC movement time
|
440.800 ± 70.397
|
550.600 ±33.557
|
0.021*
|
−215.510, -4.090
|
1.567ǂ
|
0.006**
|
43.597, 311.193
|
1.313ǂ
|
|
RTI FC reaction time
|
401.600 ± 24.419
|
401.700 ±47.429
|
0.499
|
−84.483, 84.283
|
0.002
|
0.228
|
−160.450,75.203
|
0.358
|
|
LAN
|
RTI FC movement time
|
429.600 ± 42.988
|
494.200 ±62.281
|
0.033*
|
−134.633, 5.433
|
1.391ǂ
|
0.080
|
−52.458, 294.283
|
0.691
|
|
RTI FC reaction time
|
411.500 ± 34.816
|
427.100 ±19.626
|
0.337
|
−96.876, 65.676
|
0.289
|
0.319
|
−92.282, 58.072
|
0.225
|
|
RAB
|
RTI FC movement time
|
441.400 ± 52.311
|
541.700 ±56.709
|
0.030*
|
−206.318, 5.718
|
1.427ǂ
|
0.023*
|
3.586, 332.896
|
1.012ǂ
|
|
RTI FC reaction time
|
350.900 ± 18.929
|
355.500 ±24.407
|
0.389
|
−40.606, 31.406
|
0.193
|
0.017*
|
−169.820, -7.443
|
1.081ǂ
|
|
PAN
|
RTI FC movement time
|
431.400 ± 31.271
|
558.900 ±40.799
|
0.008**
|
−226.400, -28.600
|
1.944ǂ
|
0.007**
|
43.011, 327.913
|
1.289ǂ
|
|
RTI FC reaction time
|
438.500 ± 29.655
|
459.000 ±28.355
|
0.275
|
−95.345, 54.345
|
0.413
|
0.361
|
−71.730, 101.519
|
0.170
|
|
ESO
|
RTI FC movement time
|
10.200 ± 1.618
|
9.300 ± 2.357
|
0.248
|
−178.053, 93.053
|
0.473
|
0.187
|
−91.254, 230.490
|
0.428
|
|
RTI FC reaction time
|
2.400 ± 0.562
|
2.100 ± 0.674
|
0.297
|
−127.810, 77.610
|
0.369
|
0.303
|
−99.234, 165.251
|
0.247
|
|
CON
|
RTI FC movement time
|
415.100 ± 52.731
|
371.300 ±54.126
|
0.182
|
−57.137, 140.737
|
N/A
|
|
RTI FC reaction time
|
466.600 ± 29.218
|
444.000 ±29.954
|
0.128
|
−19.658, 64.858
|
N/A
|
- Values are expressed as mean ± SEM (n=10), FC=Five-Choice, 95 % CI-D=95 % Confidence Interval of the Difference (lower, upper), p1= p value found after Paired-Samples t-test within volunteers (five test groups) before and after consuming drugs and placebo (one control group) respectively with degree of freedom (df)=9; p2= p value found after Independent-Samples t-test between each five test groups with control group having degree of freedom (df)=18. * and ** indicate statistically significant at alpha (<0.05) & (<0.01) respectively. ǂ indicates large effect size in Cohen’s d value
