Fig. 1
From: APLP1 as a cerebrospinal fluid biomarker for γ-secretase modulator treatment
Full mass spectrum of APLP1 immunoprecipitated from cerebrospinal fluid. APLP1 was immunoprecipitated from a dog or b human cerebrospinal fluid and subjected to MALDI-TOF/TOF in which a full mass spectrum was recorded. The peaks corresponding to the APLP1 peptides that have been identified by their corresponding theoretical masses or tandem mass spectrometry are annotated in the spectrum. The insert shows a magnification of the peaks detected between 1800 and 2250 m/z. Additional peaks of +16 m/z following APLP1β21 to 1β28 corresponds to oxidation of methionine at position 21. APLP1 Amyloid-like protein 1