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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: In vivo molecular neuroimaging of glucose utilization and its association with fibrillar amyloid-β load in aged APPPS1-21 mice

Fig. 7

Correlation analyses between in vivo μPET data and ex vivo measures of amyloid burden and glucose utilization. a Graph depicting [18F]FDG and [14C]2-DG quantification of brain glucose utilization. b Graph of [18F]FDG uptake versus amyloid burden. c Graph of [11C]PiB and 4G8 quantification of amyloid burden. d Graph of [18F]AV45 and 4G8 quantification of amyloid burden. Each dot represents a regional value from an individual animal (cortex, striatum, amygdala, hippocampus, thalamus, and cerebellum). Only APPPS1-21 mice were included in this analysis. μPET micro-positron emission tomography, FDG fluorodeoxyglucose, 2-DG 2-deoxy-D-glucose, PiB Pittsburgh compound B

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Alzheimer's Research & Therapy

ISSN: 1758-9193