Fig. 2

Illustrative anatomic localization of the peak voxels of rBGM reductions as measured with [18F]-FDG-PET. a1, a2 naMCI rBGM reductions in relation to the CG, predominantly in right prefrontal areas but also in the precuneus and a left prefrontal area without statistic significance; a3 naMCI rBGM reductions in relation to the aMCI group (right prefrontal area). b1, b2 Bilateral metabolic reduction in the precuneus, parietal, and temporal cortex is seen in the aMCI group in comparison with normal older subjects; b3 hypometabolism is also noted in the left temporal lobe in aMCI in relation to naMCI