Fig. 4
From: Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans
The effect of a single dose of 800 mg IV-ibuprofen on Aβ levels in humans. Plasma samples were collected at indicated time points and amyloid beta-peptide (Aβ) levels were analyzed. Ratios of Aβ42/Aβ40 (a) and Aβ42/Aβ38 (b) at baseline (before infusion) were compared among subjects. Then ratios of Aβ42/Aβ40 (c) and Aβ38/Aβ40 (d) between placebo and ibuprofen groups were compared. Results are presented as mean ± SEM