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Table 4 Descriptive statistics for plasma markers of inflammation and oxidative stress in randomized clinical trial 1

From: Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer’s disease

Marker

Baseline

Week 24

p value

CRP (mg/L)

   

 Control

1.75 [0.00, 66.90] (44)

1.80 [0.20, 58.90] (45)

0.686*

 Active

2.00 [0.10, 17.40] (47)

1.80 [0.10, 16.40] (47)

 

IL-1β (pg/ml)

   

 Control

0.24 [0.20, 0.66] (25)

0.24 [0.20, 1.48] (23)

0.309*

 Active

0.24 [0.20, 0.68] (30)

0.24 [0.20, 0.82] (25)

 

IL-6 (pg/ml)

   

 Control

2.67 [0.23, 108.3] (26)

2.59 [0.93, 6.63] (23)

0.733*

 Active

2.65 [0.26, 8.65] (31)

3.20 [0.31, 10.62] (25)

 

IL-10 (pg/ml)

   

 Control

0.91 [0.40, 2.63] (25)

1.01 [0.31, 1.72] (23)

0.799*

 Active

1.06 [0.05, 2.88] (32)

1.00 [0.11, 2.68] (27)

 

8-isoprostane (pg/ml)

   

 Control

17.78 [4.55, 80.85] (25)

22.12 [8.81, 38.40] (23)

0.071*

 Active

19.06 [6.01, 36.32] (30)

17.66 [5.73, 35.66] (25)

 

MDA (μmol/L)

   

 Control

1.23 (0.53) [45]

1.45 (0.57) [45]

0.786**

 Active

1.22 (0.56) [47]

1.48 (0.54) [47]

 
  1. CRP C-reactive protein, IL interleukin, MDA malondialdehyde
  2. Data are mean (standard deviation) [n] or median [min, max] (n)
  3. *Mann–Whitney U test, change from baseline at week 24, control vs. active
  4. **Independent samples t test, change from baseline at week 24, control vs. active