Figure 2

Absolute apolipoprotein E levels across clinical categories. Data are presented as means ± standard deviations of apolipoprotein (ApoE) levels stratified by sex and APOE-ε4 genotype in the Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL) cohort participants at the 18-month time point. One-way analysis of variance followed by post hoc Tukey’s honestly significant difference test was carried out. Healthy controls (HC): females, P < 0.001 for ε4 (F+) versus non-ε4 (F−); males, P < 0.001 for ε4 (M+) versus non-ε4 (M−). Mild cognitive impairment (MCI): females, P = 0.040 for ε4 versus non-ε4; males, P = 0.539 for ε4 versus non-ε4. Alzheimer’s disease (AD): females, P < 0.001 for ε4 versus non-ε4; males, P = 0.604 for ε4 versus non-ε4.