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Table 5 Patient characteristics at baseline: left MTA score of 0 or 1 versus 2, 3 or 4

From: The relationship of weight change trajectory with medial temporal lobe atrophy in patients with mild Alzheimer’s disease: results from a cohort study

  MTA score 0 or 1 MTA score 2, 3, 4 P
Age (year): n, median [25th -75th percentile] 16, 75.0 [72.0 - 78.8] 198, 79.0 [75.8 - 82.0] 0.003b**
Women, n (%) 11 (68.8) 121 (61.1) nsc
Social status    
 alone, n (%) 10 (62.5) 83 (43.5) nsc
 with partner, n (%) 5 (31.3) 103 (53.9)
 other*, n (%) 1 (6.3) 5 (2.6)
CIRS (score): n, median [25th -75th percentile] 16, 5.0 [4.0 - 6.0] 198, 6.0 [4.0 - 8.0] nsb
Polypharmacy, n (%) 8 (50.0) 105 (53.3) nsc
Use of informal care, n (%) 13 (81.3) 169 (85.8) nsd
Use of professional care, n (%) 6 (37.5) 93 (47.7) nsc
MMSE (score): n, median [25th -75th percentile] 16, 25.0 [23.0 - 26.8] 196, 23.0 [20.0 - 15.0] 0.017b**
Clock-drawing test (score): n, median [25th -75th percentile] 15, 3.0 [1.0 - 4.0] 178, 3.0 [2.0 -5.0] nsb
Presence of BPS, n (%) 5 (31.3) 46 (23.8) nsd
Weight (kg): n, mean ± SD 16, 68 ± 12 198, 74 ± 12 nsa
BMI (weight/(height)2): n, median [25th -75th percentile] 16, 25.7 [21.1 - 27.0] 187, 25.9 [23.5 - 29.1] nsb
Use of ONS, n (%) 0 (0.0) 1 (0.8) nsd
Appetite    
 good, n (%) 14 (87.5) 156 (93.4) nsd
 poor, n (%) 2 (12.5) 11 (6.6)
Self-reported weight loss, n (%) 2 (12.5) 26 (14.6) nsd
  1. *Other, that is: with son or daughter, brother or sister; **significant, that is P <0.05. aIndependent sample t test; bMann-Whitney U test; cPearson chi-square test; dFisher’s exact.
  2. MTA, medial temporal lobe atrophy; P, probability; n, number of patients; ns, not significant; CIRS, cumulative illness rating scale; MMSE, mini mental state examination; BPS, behavioral and psychological symptoms; SD, standard deviation; BMI, body mass index; ONS, oral nutritional supplement.